In the ancient times honey was believed to be the first sweetener used especially in some countries like China and Greece. Sugar cane then became popular from which saccharose was extracted and widely consumed by people worldwide as a regular sugar.

These days that obesity has become a great concern mostly among people of developed countries, the extent of added sugar in a wide range of food products plays an important role in raising calorie and subsequently increasing body weight. As a result, food and drug industries were encouraged to develop sugar substitute profitably.